ERN GENTURIS Webinar: Gastrointestinal polyposis syndromes

woensdag 13 januari 2021 16:00 - 17:00

Prof. Stefan Aretz

Titel: Gastrointestinal polyposis syndromes

Inhoud:Stefan Aretz is professor of Genetics of Familial Tumour Syndromes at the University of Bonn and will be the speaker of this webinar on gastrointestinal polyposis syndromes.

Several clinically characterised hereditary tumour predisposition syndromes with predominant manifestation in the gastrointestinal tract have been delineated within the last decades and explained by germline mutations in specific tumour suppressor or DNA repair genes. While some syndromes are restricted to gastrointestinal neoplasms, others show a variety of extraintestinal lesions. A clinical diagnosis might be challenging in the absence of a distinct family history and in case of a mono-symptomatic course. However, multigene panel testing can uncover those cases. For most of the polyposis syndromes, well established and efficient surveillance programs are available while in others, consensus recommendations are still lacking. This review will address state-of-the-art diagnostic algorithms and discuss present surveillance and management strategies. If you would like to attend this webinar, please, register here.

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